front page (adjective) big league: important
Sinonime: adverse,
contrary,
damaging, debit-side,
deleterious, depreciative, depreciatory,
derogatory, detracting,
disparaging, downside, dyslogistic,
harmful,
hurtful, ill-timed, inexpedient, injurious, inopportune, objectionable, on the debit side,
pejorative, prejudicial, slighting, uncomplimentary,
unfavorable, unprofitable
Antonime: advantageous,
convenient,
helpful, well-timed